Description
Metformin Hydrochloride (SR) & Glimepiride Tablets
Category: Oral Anti-Diabetic Medication
Product Description:
This combination of Metformin Hydrochloride (Sustained Release) and Glimepiride is designed for the effective management of Type 2 Diabetes Mellitus. By helping to regulate blood glucose levels, it aids in controlling diabetes and preventing long-term complications such as cardiovascular disease, kidney issues, and nerve damage.
Composition:
- Metformin Hydrochloride (SR) 500 mg/1000 mg: Belonging to the biguanide class, Metformin reduces liver glucose production, improves insulin sensitivity, and delays glucose absorption in the intestines.
- Glimepiride 1 mg/2 mg: A sulfonylurea that promotes the release of insulin from pancreatic beta cells, helping lower blood glucose levels.
Indications:
- Treatment of Type 2 Diabetes Mellitus in adults, especially where diet and exercise alone are insufficient.
- As monotherapy or in combination with other oral anti-diabetic agents or insulin, for better glycemic control.
Key Features:
- Dual mechanism of action: Metformin helps reduce glucose production in the liver, while Glimepiride enhances insulin secretion from the pancreas.
- Sustained Release (SR) formulation: Provides a prolonged effect of Metformin throughout the day, leading to better glycemic control.
- Reduces HbA1c levels and improves long-term blood sugar control.
- Convenient once-daily dosing for better patient compliance.
Dosage:
- Typical dosage: One tablet once or twice a day, depending on the individual’s glycemic response.
- Adjustments should be made based on blood glucose levels and under physician supervision.
Precautions:
- Not recommended for patients with severe renal or hepatic impairment.
- Caution in elderly or malnourished patients, as they may be more susceptible to hypoglycemia.
- Regular blood sugar monitoring is essential.
- Avoid excessive alcohol intake during treatment.
Side Effects:
- Common: Low blood sugar (hypoglycemia), nausea, upset stomach, diarrhea
- Rare: Allergic reactions, lactic acidosis (linked to Metformin)
Contraindications:
- Type 1 Diabetes
- Diabetic ketoacidosis
- Severe kidney or liver problems
Storage:
- Store in a cool, dry place, away from heat and moisture.
- Keep out of reach of children.
