Description
Metformin Hydrochloride (SR) & Glimepiride Tablets I.P
Category: Oral Anti-Diabetic Medication
Product Description:
Metformin Hydrochloride (SR) & Glimepiride Tablets I.P are designed for the effective management of Type 2 Diabetes Mellitus. This combination medication leverages the complementary mechanisms of action of Metformin, a biguanide, and Glimepiride, a sulfonylurea, to provide optimal glycemic control and improve the patient’s overall health.
Composition:
- Metformin Hydrochloride (SR) 500 mg/1000 mg: A biguanide that decreases hepatic glucose production, improves insulin sensitivity, and enhances peripheral glucose uptake and utilization.
- Glimepiride 1 mg/2 mg: A sulfonylurea that stimulates insulin release from pancreatic beta cells, helping to lower blood glucose levels effectively.
Indications:
- Management of Type 2 Diabetes Mellitus in adults, particularly when diet and exercise alone are insufficient.
- Can be used alone or in combination with other oral anti-diabetic medications or insulin for improved glycemic control.
Key Features:
- Dual-action formulation: Metformin controls glucose production and enhances insulin sensitivity, while Glimepiride stimulates insulin secretion, offering a synergistic effect.
- Sustained Release (SR): The Metformin formulation ensures a gradual release of the medication, providing prolonged action and better control of blood glucose levels throughout the day.
- Helps in reducing HbA1c levels, improving overall blood sugar management, and minimizing the risk of long-term diabetes complications.
Dosage:
- Typical dosage: One tablet once or twice daily, depending on the severity of the condition and individual patient needs.
- Dosage adjustments should be based on the patient’s glycemic response and under the supervision of a healthcare professional.
Precautions:
- Not recommended for use in patients with severe renal or hepatic impairment.
- Regular monitoring of blood glucose levels is essential to avoid potential hypoglycemia.
- Caution in elderly patients or those with a history of hypoglycemia.
Side Effects:
- Common: Nausea, vomiting, diarrhea, headache, dizziness
- Rare: Lactic acidosis (with Metformin), allergic reactions, hypoglycemia (with Glimepiride)
Contraindications:
- Type 1 Diabetes Mellitus
- Diabetic ketoacidosis
- Severe renal or hepatic impairment
Storage:
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
Note: Always take the medication as prescribed by your healthcare provider. Inform your doctor of any other medications you are taking to prevent potential interactions and complications.
